Indacaterol maleate

Overview
Catalog #	bs-83767c-10mg
Product Name	Indacaterol maleate
Specifications
Storage Buffer	White to off-white solid
Storage Condition	-20°C
Target
Product Information	Indacaterol maleate is a full agonist (pEC50 = 8.06) of the human ß2 adrenoceptor.1,2 Clinically important drug for the treatment of chronic obstructive pulmonary disease. Indacaterol blocked colorectal cancer progression in vitro (IC50 = 19.01 µM) and in vivo via inhibition of the splicing factor SRSF6 by binding to its RRM2 domain.3 It also blocked cell migration in metastatic breast cancer MDA-MB-231 cells by a similar mechanism.4
Description	CAS Number: 753498-25-8 Chemical Name: 5-[(1R)-2-[(5,6-Diethyl-2,3-dihydro-1H-inden-2-yl)amino]-1-hydroxyethyl]-8-hydroxy-1H-quinolin-2-one maleate salt Molecular Weight: 508.57 Formula: C24H28N2O3·C4H4O4 Solubility: DMSO (>25 mg/ml) Physical Properties: White to off-white solid Purity: >98% by HPLC NMR (Conforms)